Deeptech companies aim to address the world’s biggest challenges. Nedayvoda, et al. (2020) write that a deep tech company brings transformative technology from the lab to the market, and that democratized research infrastructure and increased available funding has led to the rise of deeptech companies globally, including in emerging markets. Commercialization is critical to realizing the benefits of deep tech solutions, and deeptech firms often struggle to successfully commercialize their breakthroughs¹. This commentary paper aims to find the current barriers that deeptech companies have to break through worldwide, as a start to discuss policy and private interventions in future papers.